Drugs included in Gene2Rx Report
The following drugs are included in the Gene2Rx report. Each drug has pharmacogenetic prescription guidance on
it's drug label from the US Food and Drug Administration (FDA) or a published guideline by the Clinical Pharmacogenomics Implementation Consoritium (CPIC)
which provides prescription guidance to clinicians based on your genetics.
Gene2Rx analyzes your DNA and detects genetic variations that may lead to an atypical response to these
medications. We provide predictions for the 46 medications listed here. For therapeutic recommendations consult
the CPIC guideline associated with the drug and phenotype in your report. Always consult your health care
provider before making medical decisions.
Antiarrhythmics
|
|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Propafenone |
Rythmol Sr |
CYP2D6 |
FDA |
Anticonvulsants
|
|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Brivaracetam |
Briviact |
CYP2C19 |
FDA |
Clobazam |
Onfi, Frisium |
CYP2C19 |
FDA |
Fosphenytoin |
Cerebyx |
CYP2C9 |
CPIC |
Phenytoin |
Dilantin |
CYP2C9 |
CPIC |
Antidepressants - SNRI
|
|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Venlafaxine |
Effexor Xr |
CYP2D6 |
FDA |
Antidepressants - SSRI
|
|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Citalopram |
Celexa, Cipralex, Lexapro |
CYP2C19 |
CPIC, FDA |
Escitalopram |
Lexapro |
CYP2C19 |
CPIC |
Fluvoxamine |
Luvox |
CYP2D6 |
CPIC |
Paroxetine |
Paxil, Seroxat |
CYP2D6 |
CPIC |
Sertraline |
Zoloft |
CYP2C19 |
CPIC |
Vortioxetine |
Trintellix, Brintellix |
CYP2D6 |
FDA |
Antidepressants - TCA
|
|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Amitriptyline |
Elavil |
CYP2C19, CYP2D6 |
CPIC |
Clomipramine |
Anafranil |
CYP2C19, CYP2D6 |
CPIC |
Desipramine |
Norpramin |
CYP2D6 |
CPIC |
Doxepin |
Sinequan, Quitaxon, Aponal |
CYP2C19, CYP2D6 |
CPIC |
Imipramine |
Tofranil |
CYP2C19, CYP2D6 |
CPIC |
Nortriptyline |
Pamelor |
CYP2D6 |
CPIC |
Trimipramine |
Surmontil |
CYP2C19, CYP2D6 |
CPIC |
Antiemetics
|
|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Dronabinol |
Syndros |
CYP2C9 |
FDA |
Metoclopramide |
Reglan |
CYP2D6 |
FDA |
Ondansetron |
Zofran |
CYP2D6 |
CPIC |
Tropisetron |
Navoban |
CYP2D6 |
CPIC |
Antifungals
|
|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Voriconazole |
Vfend |
CYP2C19 |
CPIC
|
Antihistimines
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|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Meclizine |
Antivert |
CYP2D6 |
FDA |
Antipsychotics
|
|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Aripiprazole |
Abilify |
CYP2D6 |
FDA |
Aripiprazole Lauroxil |
Aristada |
CYP2D6 |
FDA |
Brexpiprazole |
Rexulti |
CYP2D6 |
FDA |
Iloperidone |
Fanapt |
CYP2D6 |
FDA |
Perphenazine |
Trilafon |
CYP2D6 |
FDA |
Pimozide |
Orap |
CYP2D6 |
FDA |
Antiretrovirals
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|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Atazanavir |
Reyataz, Evotaz, Others |
UGT1A1 |
CPIC
|
Efavirenz |
Sustiva |
CYP2B6 |
CPIC, FDA |
Antivirals
|
|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Peginterferon Alfa-2a |
Pegasys |
IFNL3 |
CPIC |
Peginterferon Alfa-2b |
Pegintron |
IFNL3 |
CPIC |
Ribavirin |
Copegus, Rebetol, Virazole |
IFNL3 |
CPIC |
Beta Blockers
|
|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Carvedilol |
Coreg, Coreg Cr |
CYP2D6 |
FDA |
Blood Thinners
|
|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Clopidogrel |
Plavix |
CYP2C19 |
CPIC |
Warfarin |
Coumadin |
CYP2C9, CYP4F2, VKORC1 |
CPIC, FDA |
Chemotherapies
|
|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Belinostat |
Beleodaq |
UGT1A1 |
FDA |
Capecitabine |
Xeloda, Xitabin, Kapetral |
DPYD |
CPIC, FDA |
Erdafitinib |
Balversa |
CYP2C9 |
FDA |
Fluorouracil |
Adrucil, Carac |
DPYD |
CPIC, FDA |
Gefitinib |
Iressa |
CYP2D6 |
FDA |
Irinotecan |
Camptosar, Onivyde |
UGT1A1 |
FDA |
Mercaptopurine |
Purinethol |
NUDT15, TPMT |
CPIC
|
Nilotinib |
Tasigna |
UGT1A1 |
FDA |
Pazopanib |
Votrient |
UGT1A1 |
FDA |
Thioguanine |
Lanvis, Tabloid |
NUDT15, TPMT |
CPIC,
FDA |
Cholesterol Medications
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|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Simvastatin |
Zocor |
SLCO1B1 |
CPIC,
FDA |
Drugs Used In Addictive Disorders
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|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Lofexidine |
Lucemyra |
CYP2D6 |
FDA |
Estrogen Modulators
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|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Tamoxifen |
Nolvadex, Soltamox |
CYP2D6 |
CPIC |
Female Sexual Health
|
|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Flibanserin |
Addyi |
CYP2C19 |
FDA |
Gaucher's Disease Treatments
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|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Eliglustat |
Cerdelga |
CYP2D6 |
FDA |
Immunosuppressants
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|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Azathioprine |
Imuran |
NUDT15, TPMT |
CPIC,
FDA |
Mercaptopurine |
Purinethol |
NUDT15, TPMT |
FDA |
Siponimod |
Mayzent |
CYP2C9 |
FDA |
Tacrolimus |
Prograf |
CYP3A5 |
CPIC,
FDA |
Involuntary Movement Reducers
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|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Deutetrabenazine |
Austedo |
CYP2D6 |
FDA |
Tetrabenazine |
Xenazine |
CYP2D6 |
FDA |
Valbenazine |
Ingrezza |
CYP2D6 |
FDA |
Pain Management
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|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Celecoxib |
Celebrex |
CYP2C9 |
CPIC, FDA |
Codeine |
Tylenol 3 |
CYP2D6 |
CPIC, FDA |
Flurbiprofen |
Ansaid, Ocufen, Strepfen |
CYP2C9 |
CPIC, FDA |
Ibuprofen |
Advil |
CYP2C9 |
CPIC |
Lornoxicam |
Xefo |
CYP2C9 |
CPIC |
Meloxicam |
Mobic |
CYP2C9 |
CPIC |
Piroxicam |
Feldene |
CYP2C9 |
CPIC, FDA |
Tenoxicam |
Mobiflex |
CYP2C9 |
CPIC |
Tramadol |
Ultram, Conzip |
CYP2D6 |
CPIC |
Proton Pump Inhibitors
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|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Dexlansoprazole |
Dexilant |
CYP2C19 |
CPIC |
Lansoprazole |
Prevacid |
CYP2C19 |
CPIC |
Omeprazole |
Prilosec, Losec |
CYP2C19 |
CPIC |
Pantoprazole |
Protonix |
CYP2C19 |
CPIC, FDA |
Psychostimulants
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|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Amphetamine |
Adzenys Er |
CYP2D6 |
FDA |
Atomoxetine |
Strattera |
CYP2D6 |
CPIC, FDA |
Saliva Production Stimulators
|
|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Cevimeline |
Evoxac |
CYP2D6 |
FDA |
Urologicals
|
|
|
|
Generic name |
Brand names |
Genes tested |
Source |
Tolterodine |
Detrol |
CYP2D6 |
FDA |